Resumo
Objetivo: verificar associação do declínio cognitivo e dos fatores socioeconômicos com o risco cardiovascular em idosos com Alzheimer. Método: estudo transversal, em que se incluíram 75 idosos com Alzheimer. Verificaram-se pressão de pulso, risco cardiovascular, Miniexame do Estado Mental, Miniavaliação Nutricional e exames bioquímicos. Resultados: 92% dos pacientes apresentaram declínio cognitivo, com média de três anos de escolaridade. Houve prevalência entre as mulheres (62,3%) e idosos com duas ou mais comorbidades (62,3%). Eram hipertensos (65,2%), estavam com a pressão de pulso elevada (85%), com sobrepeso (49%) e em risco nutricional (78%). Média diária de dois anti-hipertensivos, e a classe medicamentosa mais utilizada foi bloqueador do receptor da angiotensina. Conclusão: a população estudada apresentou risco cardiovascular aumentado. A consulta de enfermagem foi importante para o reconhecimento dos dados clínicos, como declínio cognitivo, risco cardiovascular, risco nutricional e análise bioquímica.
Referências
de Heus RAA, Olde Rikkert MGM, Tully PJ, Lawlor BA, Claassen JAHR, NILVAD Study Group. Blood pressure variability and progression of clinical Alzheimer disease. Hypertension. 2019;74(5):1172-80. http://dx.doi.org/10.1161/HYPERTENSIONAHA.119.13664. PMid:31542965.
Silva MVF, Loures CMG, Alves LCV, de Souza LC, Borges KBG, Carvalho MDG. Alzheimer’s disease: risk factors and potentially protective measures. J Biomed Sci. 2019;26(33):33. http://dx.doi.org/10.1186/s12929-019-0524-y. PMid:31072403.
Scheyer O, Rahman A, Hristov H, Berkowitz C, Isaacson RS, Diaz Brinton R, et al. Female sex and Alzheimer’s risk: the menopause connection. J Prev Alzheimers Dis. 2018;5(4):225-30. http://dx.doi.org/10.14283/jpad.2018.34. PMid:30298180.
Pelazza BB, Ferreira SR Fo. Comparison between central and brachial blood pressure in hypertensive elderly women and men. Int J Hypertens. 2017;2017:e6265826. http://dx.doi.org/10.1155/2017/6265823.
Barroso WKS, Rodrigues CIS, Bortolotto LA, Mota-Gomes MA, Brandão AA, Feitosa ADM, et al. Diretrizes Brasileiras de Hipertensão Arterial–2020. Arq Bras Cardiol. 2021;116(3):516-658. http://dx.doi.org/10.36660/abc.20201238. PMid:33909761.
Niiranen TJ, Kalesan B, Mitchell GF, Vasan RS. Relative contributions of pulse pressure and arterial stiffness to cardiovascular disease: the framingham heart study. Hypertension. 2019;73(3):712-7. http://dx.doi.org/10.1161/HYPERTENSIONAHA.118.12289. PMid:30661478.
van Middelaar T, van Dalen JW, van Gool WA, van den Born BJH, van Vught LA, Moll van Charante EP, et al. Visit-to-visit blood pressure variability and the risk of dementia in older people. J Alzheimers Dis. 2018;62(2):727-35. http://dx.doi.org/10.3233/JAD-170757. PMid:29480175.
Brasil. Ministério da Saúde. Envelhecimento e saúde da pessoa idosa [Internet]. Brasília: Ministério da Saúde; 2006. (Cadernos de Atenção Básica; 19). [cited 2021 Oct 8]. Available from: http://189.28.128.100/dab/docs/publicacoes/cadernos_ab/abcad19.pdf
Oliveira MR, Almeida PC, Moreira TMM, Torres RAM. Nursing care systematization: perceptions and knowledge of the Brazilian nursing. Rev Bras Enferm. 2019;72(6):1625-31. http://dx.doi.org/10.1590/0034-7167-2018-0606. PMid:31644743.
Barros M, Zamberlan C, Gehlen MH, Rosa PH, Ilha S. Awareness raising workshop for nursing students on the elderly with Alzheimer’s disease: contributions to education. Rev Bras Enferm. 2020;73(Suppl 3):e20190021. http://dx.doi.org/10.1590/0034-7167-2019-0021. PMid:32696903.
Brasil. Ministério da Saúde. Vigilância alimentar e nutricional – Sisvan: orientações básicas para a coleta, processamento, análise de dados e informação em serviços de saúde [Internet]. Brasília: Ministério da Saúde; 2004 [cited 2022 Feb 24]. Available from: http://tabnet.datasus.gov.br/cgi-win/SISVAN/CNV/notas_sisvan.html#:~:text=Valores%20de%20IMC%20menor%20ou,%2C0%3A%20idoso%20com%20sobrepeso
Ferreira JDL, Soares MJGO, Lima CLJ, Ferreira TMC, Oliveira PS, Silva MA. Evaluación nutricional por el Mini Nutritional Assessment: una herramienta para las enfermeras. Enferm Glob. 2018;17(3):267-305. http://dx.doi.org/10.6018/eglobal.17.3.290251.
Yu JT, Xu W, Tan CC, Andrieu S, Suckling J, Evangelou E, et al. Evidence-based prevention of Alzheimer’s disease: systematic review and meta-analysis of 243 observational prospective studies and 153 randomised controlled trials. J Neurol Neurosurg Psychiatry. 2020;91(11):1201-9. https://doi.org/10.1136/jnnp-2019-321913. PMID: 32690803.
Roman MJ, Devereux RB, Kizer JR, Okin PM, Lee ET, Wang W, et al. High central pulse pressure is independently associated with adverse cardiovascular outcome the strong heart study. J Am Coll Cardiol. 2009;54(18):1730-4. http://dx.doi.org/10.1016/j.jacc.2009. 05.070. PMid:19850215.
Li X, Leng S, Song D. Link between type 2 diabetes and Alzheimer’s disease: from epidemiology to mechanism and treatment. Clin Interv Aging. 2015;10:549-60. http://dx.doi.org/10.2147/CIA.S74042. PMid:25792818.
Profenno LA, Porsteinsson AP, Faraone SV. Meta-analysis of Alzheimer’s disease risk with obesity, diabetes, and related disorders. Biol Psychiatry. 2010;67(6):505-12. http://dx.doi.org/10.1016/j.biopsych.2009.02.013. PMid:19358976.
Qu Y, Hu HY, Ou YN, Shen XN, Xu W, Wang ZT, et al. Association of body mass index with risk of cognitive impairment and dementia: a systematic review and meta-analysis of prospective studies. Neurosci Biobehav Rev. 2020;115:189-98. http://dx.doi.org/10.1016/j.neubiorev.2020.05.012. PMid:32479774.
Smith PJ, Blumenthal JA. Diet and neurocognition: review of evidence and methodological considerations. Curr Aging Sci. 2010;3(1):57-66. http://dx.doi.org/10.2174/1874609811003010057.
Hagström E, Kilander L, Nylander R, Larsson EM, Michaëlsson K, Melhus H, et al. Plasma parathyroid hormone is associated with vascular dementia and cerebral hyperintensities in two community-based cohorts. J Clin Endocrinol Metab. 2014;99(11):4181-9. http://dx.doi.org/10.1210/jc.2014-1736. PMid:25140397.
Larsson SC, Traylor M, Markus HS, Michaëlsson K. Serum parathyroid hormone, 25-hydroxyvitamin D, and risk of Alzheimer’s disease: a Mendelian randomization study. Nutrients. 2018;10(9):1243. http://dx.doi.org/10.3390/nu10091243. PMid:30200567.
Watanabe Y, Hirao Y, Kasuga K, Tokutake T, Kitamura K, Niida S, et al. Urinary apolipoprotein c3 is a potential biomarker for alzheimer’s disease. Dement Geriatr Cogn Dis Extra. 2020;10(3):94-104. http://dx.doi.org/10.1159/000509561. PMid:33082773.

Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.
Copyright (c) 2022 Array