Clinical, epidemiological and survival profile of transplant recipients with hematopoietic stem cells: a retrospective cohort
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Keywords

Survival Analysis
Delivery of Health Care
Epidemiology
Hemtopoietic Stem Cell Transplantation
Bone Marrow Transplantation Análisis de Supervivencia
Prestación de Atención de Salud
Epidemiología
Trasplante de Células Madre Hematopoyéticas
Trasplante de Médula Ósea Análise de Sobrevida
Assistência à Saúde
Epidemiologia
Transplante de Células-Tronco Hematopoéticas
Transplante de Medula Óssea

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Abstract

Aim: to characterize the clinical and epidemiological profile of patients who underwent hematopoietic stem cell transplantation (HSCT) and to estimate the overall survival of transplant recipients. Method: this is a quantitative approach study, of the retrospective cohort, descriptive and analytical type, hospital-based with 272 patients who underwent HSCT in a referral service. Results: the profile of the patients presented a discrete male prevalence. The overall survival of transplanted patients showed a statistically significant difference when compared according to sex. Concerning death, the majority occurred in male patients, with a statistically significant difference for those who had been followed for more than seven months and for those who presented acute lymphoblastic leukemia as the main indicative diagnosis for HSCT. Conclusion: in relation to clinical variables, the results were similar to those found in similar studies; however, survival rates were relatively low.
https://doi.org/10.17665/1676-4285.20175970
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References

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Henig I, Zuckerman T. Hematopoietic Stem Cell Transplantation—50 Years of Evolution and Future Perspectives. Rambam Maimonides Med J [Internet]. 2014 [cited 2016 Nov 07]; 5 (4): 1-15. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222417/pdf/rmmj-5-4-e0028.pdf

Reis M, Ogonek J, Marsela Qesari, Borges NM, Nicholson L, Preußner L, et al. Recent developments in cellular immunotherapy for HSCT-associated complications. Front Immunol [internet]. 2016 [cited 2016 Nov 07]; 7 (500): 1-28. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107577/pdf/fimmu-07-00500.pdf