Hypothesis: There is no hypoxemia after tracheal aspiration when there is no optimization of O2 pre-aspiration. Aim: To verify, through the assessment of arterial gasometry, if there is a significant difference in the values of SaO2, PaO2 and P/F in patients on ventilatory assistance and septic shock when FiO2 is not kept to 100% after tracheal aspiration. Methodology: a randomized clinical trial-type crossover, with two interventions, one arm, double-blind, phase III. A convenience sample of 27 patients is used by calculation for discrete variables of finite populations. Inclusion criteria: septic shock due to local infection, mechanical ventilation for more than 12 hours, optimal FiO2 <95%, PEEP <24 mmHg. For the statistical analysis we will use the student`s t-test with a significance level of 5% supported by software R version 2.5.1
Martins I, Gutiérrez MGR. Nursing interventions for the nursing diagnosis ineffective airway clearance. Acta Paul Enferm. 2005;18(2):143-9
Rodrigues MVH. Estudo do comportamento hemodinâmico, da troca gasosa, mecânica, respiratória e da análise do muco brônquico na aplicação de técnicas de remoção de secreção brônquica em pacientes sob ventilação mecânica. Tese [doutorado em Cardiologia]. Universidade de São Paulo; 2007.
Lima, DVM. Design of research: a contribution for authors. Online Braz J of Nursing. [serial on the Internet]. 2011 Oct; [cited 2012 Aug 3]; 10(2). Available from: http://www.objnursing.uff.br/index.php/nursing/article/view/3648