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Platelet-rich plasma in the treatment of venous ulcers: case series

Beatriz Guitton Renaud Baptista de Oliveira, Silvia Regina Secoli, Andrea Pinto Leite Ribeiro, Alcione Matos de Abreu, Jane Marcy Neffá Pinto


Objective: To assess the viability of the treatment of venous ulcers with platelet-rich plasma (PRP). Method: A descriptive case series study conducted as a pilot study for a clinical trial. With a sample of three patients, allocated after randomization, two for intervention and one for control. The direct cost was collected by means of direct observation. Results: In patients who received the intervention (PRP), two venous ulcers were followed-up, one presented complete healing, with a cost of US$ 550.35, and the other exhibited a rate of area reduction of 33.33%, with a cost of US$ 1,070.32. In the control patient, there was an 83.33% reduction in the venous ulcer area, with a cost of US$ 361,53. Discussion: The pilot test made it possible to adequate the protocols and to determine the supplies required for the completion of the study. Conclusion: The assessment of the clinical protocols is pivotal for the development of controlled clinical trials.


Platelet-Rich Plasma; Varicose Ulcer; Nursing; Technology Assessment, Biomedical; Costs and Cost Analysis; Cost-Effectiveness Evaluation;


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