Keywords
Diagnosis
Molecular Diagnostic Techniques
Rapid Diagnostic Tests
How to Cite
Abstract
Objective: to synthesize the scientific knowledge produced on the accuracy of the rapid molecular test in the diagnosis of extrapulmonary tuberculosis. Method: This is a systematic review protocol, whose research question was drawn up using the PIRD strategy (where Population (P) corresponds to people of any age; Index Test (I), to the molecular rapid test (Gene Xpert MTB/RIF and/or Gene Xpert Ultra); Reference Test (R), to culture; Diagnosis (D), to extrapulmonary tuberculosis). Literature searches were carried out using controlled and free vocabularies in five scientific literature databases and two gray literature sites. The results found were exported to the Qatar Computing Research Institute's (QCRI) Rayyan software (scientific literature) and word files (grey literature), through which it will be possible to exclude duplicate material and the selection of publications by three reviewers. The data from the selected publications will be extracted using a spreadsheet based on the recommendations of the Joanna Briggs Institute (JBI), which also has an instrument for assessing the methodological quality of studies on the accuracy of diagnostic tests, which will be used in this review. The results of the studies will be synthesized narratively and by means of meta-analysis.
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