Cost-effectiveness of the treatment of sickle cell anemia with hydroxyurea: an economic evaluation study

Abstract

Objective: to analyze the cost-effectiveness of the treatment of sickle cell anemia (SCA) using hydroxyurea. Method: economic evaluation study, with a quantitative, descriptive and analytical approach, through a retrospective cohort. To be developed in the main reference services in Campo Grande/MS. Through three phases: systematic literature review, with analysis by odds ratio, model of inverse random effect and chi-square; secondary data collection from medical records and DATASUS with chi-square analysis or Fisher’s exact test; cost-effectiveness analysis using the Markov analytical decision model and Student's t test for all variables. This research is approved by the UFMS Ethics Committee, under opinion no. 2,892,100. Expected results: Produce indicators to support the improvement of public policies, assist in decision-making and therapeutic conduct, in addition to promoting the improvement of patients' quality of life.